IFOM

Selected Publications Stefano Piccolo

  1. Yui S, Azzolin L,Maimets M, Pedersen MT,Fordham RP, Hansen SL, Larsen HL,Guiu J, Alves MRP, Rundsten CF,Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB.
    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.
    Cell Stem Cell (2018), 22(1):35-49.

  2. Panciera T, Azzolin L, Cordenonsi M, Piccolo S.
    Mechanobiology of YAP and TAZ in physiology and disease.
    Nat Rev Mol Cell Biol (2017), 18(12):758-770.

  3. Totaro A, Castellan M, Battilana G, Zanconato F, Azzolin L, Giulitti S, Cordenonsi M, Piccolo S.
    YAP/TAZ link cell mechanics to Notch signaling to control epidermal stem cell fate.
    Nat Commun (2017), 8:15206

  4. Zanconato, F., Cordenonsi, M., Piccolo, S.
    YAP/TAZ at the Roots of Cancer
    (2016), Cancer Cell, 29 (6), pp. 783-803.

  5. Panciera T, Azzolin L, Fujimura A, Di Biagio D, Frasson C, Bresolin S, Soligo S, Basso G, Bicciato S, Rosato A, Cordenonsi M, Piccolo S.
    Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.
    Cell Stem Cell (2016), 19(6):725-737.

  6. Zanconato F, Forcato M, Battilana G, Azzolin L, Quaranta E, Bodega B, Rosato A, Bicciato S, Cordenonsi M, Piccolo S.
    Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth.
    Nat Cell Biol. (2015), 17(9):1218-27

  7. Sorrentino, G., Ruggeri, N., Specchia, V., Cordenonsi, M., Mano, M., Dupont, S., Manfrin, A., Ingallina, E., Sommaggio, R., Piazza, S., Rosato, A., Piccolo, S., Del Sal, G.
    Metabolic control of YAP and TAZ by the mevalonate pathway
    (2014) Nature Cell Biology, 16 (4), pp. 357-366.

  8. Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S, Frasson C, Basso G, Guzzardo V, Fassina A, Cordenonsi M, Piccolo S.
    YAP/TAZ incorporation in the b-catenin destruction complex orchestrates the Wnt response.
    Cell (2014), 158 (1): 157-70

  9. Aragona, M., Panciera, T., Manfrin, A., Giulitti, S., Michielin, F., Elvassore, N., Dupont, S., Piccolo, S.
    A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors
    (2013) Cell, 154 (5), pp. 1047-1059.

  10. Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S.
    Role of TAZ as mediator of Wnt signaling.
    Cell (2012) 151(7):1443-56

  11. Montagner, M., Enzo, E., Forcato, M., Zanconato, F., Parenti, A., Rampazzo, E., Basso, G., Leo, G., Rosato, A., Bicciato, S., Cordenonsi, M., Piccolo, S.
    SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors
    (2012) Nature, 487 (7407), pp. 380-384.

  12. Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S.
    The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells.
    Cell (2011) 147, 759–772

  13. Inui, M., Manfrin, A., Mamidi, A., Martello, G., Morsut, L., Soligo, S., Enzo, E., Moro, S., Polo, S., Dupont, S., Cordenonsi, M., Piccolo, S.
    USP15 is a deubiquitylating enzyme for receptor-activated SMADs
    (2011) Nature Cell Biology, 13 (11), pp. 1368-1375.

  14. Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Zanconato F, Le Digabel J, Forcato M, Elvassore N and Piccolo S (2011).
    Role of YAP/TAZ in mechanotransduction.
    Nature 474: 179-183

  15. Morsut, L., Yan, K.-P., Enzo, E., Aragona, M., Soligo, S.M., Wendling, O., Mark, M., Khetchoumian, K., Bressan, G., Chambon, P., Dupont, S., Losson, R., Piccolo, S.
    Negative control of Smad activity by ectodermin/Tif1β patterns the mammalian embryo
    (2010) Development, 137 (15), pp. 2571-2578.

  16. Martello, G., Rosato, A., Ferrari, F., Manfrin, A., Cordenonsi, M., Dupont, S., Enzo, E., Guzzardo, V., Rondina, M., Spruce, T., Parenti, A.R., Daidone, M.G., Bicciato, S., Piccolo, S.
    A microRNA targeting dicer for metastasis control
    (2010) Cell, 141 (7), pp. 1195-1207.

  17. Adorno, M., Cordenonsi, M., Montagner, M., Dupont, S., Wong, C., Hann, B., Solari, A., Bobisse, S., Rondina, M.B., Guzzardo, V., Parenti, A.R., Rosato, A., Bicciato, S., Balmain, A., Piccolo, S.
    A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis
    (2009) Cell, 137 (1), pp. 87-98.

  18. Dupont, S., Mamidi, A., Cordenonsi, M., Montagner, M., Zacchigna, L., Adorno, M., Martello, G., Stinchfield, M.J., Soligo, S., Morsut, L., Inui, M., Moro, S., Modena, N., Argenton, F., Newfeld, S.J., Piccolo, S.
    FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination
    (2009) Cell, 136 (1), pp. 123-135.

  19. Cordenonsi, M., Montagner, M., Adorno, M., Zacchigna, L., Martello, G., Mamidi, A., Soligo, S., Dupont, S., Piccolo, S.
    Integration of TGF-β and Ras/MAPK signaling through p53 phosphorylation
    (2007) Science, 315 (5813), pp. 840-843.

  20. Martello, G., Zacchigna, L., Inui, M., Montagner, M., Adorno, M., Mamidi, A., Morsut, L., Soligo, S., Tran, U., Dupont, S., Cordenonsi, M., Wessely, O., Piccolo, S.
    MicroRNA control of Nodal signalling
    (2007) Nature, 449 (7159), pp. 183-188.