Matteo Cereda Lab

Matteo Cereda

Matteo Cereda graduated in Biomedical Engineering from the Polytechnic University of Milan in 2005 and began his research career as a junior fellow at the IRCCS E. Medea Institute (Bosisio Parini, IT), where he modeled the impact of genetic variation on alternative splicing. He obtained a Ph.D. in Complex Systems in Genomics from the University of Turin in 2010, during which he trained in Jernej Ule’s group at the MRC Laboratory of Molecular Biology (Cambridge, UK), focusing on protein–RNA interactions. read more

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RNA regulatory networks in translation oncology

The regulation of RNA production is a fundamental determinant of cellular identity, and its dysregulation plays a pivotal role in cancer progression and therapeutic resistance. Our research seeks to decode the regulatory networks that control the production of aberrant RNAs, with the ultimate goal of enabling the development of RNA-based therapies. read more

Laboratory location: Milan, Italy

Previous publications

RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade
Nokin MJ, Mira A, Patrucco E, Ricciuti B, Cousin S, Soubeyran I, San José S, Peirone S, Caizzi L, Vietti Michelina S, Bourdon A, Wang X, Alvarez-Villanueva D, Martínez-Iniesta M, Vidal A, Rodrigues T, García-Macías C, Awad MM, Nadal E, Villanueva A, Italiano A*, Cereda M*, Santamaría D*, Ambrogio C*.
Nat Commun. 2024 Aug 30;15(1):7554. PMID: 39215000

FOXA1 regulates alternative splicing in prostate cancer.
Del Giudice M°, Foster JG°, Peirone S, Rissone A, Caizzi L, Gaudino F, Parlato C, Anselmi F, Arkell R, Guarrera S, Oliviero S, Basso G, Rajan P*, Cereda M*.
Cell Rep. 2022 Sep 27;40(13):111404. doi: 10.1016/j.celrep.2022.111404 PMID: 36170835

Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles.
Lauria A.°, Peirone S.°, Giudice M.D.°, Priante F., Rajan P., Caselle M., Oliviero S.*, Cereda M.*
Nucleic Acids Research. 2020. Vol:48 Issue:4 doi:10.1093/nar/gkz1208 ISSN:03051048 PMID: 31889184

PubMed

Group members - University of Milan

Researcher Fellow

Gabriele Boscagli

SEMM PhD Student

Tommaso Becchi
Federica Giuliano, MD
Mariachiara Grieco

Master Thesis Student

Erika Ballabio
Laura Ruffoni

(update: Oct 2025)