IFOM

Publications 2024

last update May 2025
  1. Adding fasting-mimicking diet to first-line carboplatin-based chemotherapy is associated with better overall survival in advanced triple-negative breast cancer patients: A subanalysis of the NCT03340935 trial
    Ligorio F, Lobefaro R, Fucà G, Provenzano L, Zanenga L, Nasca V, Sposetti C, Salvadori G, Ficchì A, Franza A, Martinetti A, Sottotetti E, Formisano B, Depretto C, Scaperrotta G, Belfiore A, Vingiani A, Ferraris C, Pruneri G, de Braud F, Vernieri C.
    (2024) Int J Cancer. 2024 Jan 1;154(1):114-123. doi: 10.1002/ijc.34701. Epub 2023 Aug 24. [37615485]

  2. Circulating biomarkers in familial cerebral cavernous malformation
    Lazzaroni F, Meessen JMTA, Sun Y, Lanfranconi S, Scola E, D'Alessandris QG, Tassi L, Carriero MR, Castori M, Marino S, Blanda A, Nicolis EB, Novelli D, Calabrese R, Agnelli NM, Bottazzi B, Leone R, Mazzola S, Besana S, Catozzi C, Nezi L, Lampugnani MG, Malinverno M, Grdseloff N, Rödel CJ, Rezai Jahromi B, Bolli N, Passamonti F, Magnusson PU, Abdelilah-Seyfried S, Dejana E, Latini R.
    (2024) EBioMedicine. 2024 Jan;99:104914. doi: 10.1016/j.ebiom.2023.104914. Epub 2023 Dec 18. [38113759]

  3. Nutrition and dietary restrictions in cancer prevention
    Mishra A, Giuliani G, Longo VD.
    (2024)Biochim Biophys Acta Rev Cancer. 2024 Jan;1879(1):189063. doi: 10.1016/j.bbcan.2023.189063. Epub 2023 Dec 24. [38147966]

  4. Enrichment of DNA replication intermediates by EdU pull down
    Pessina F, Romussi A, Piccini D, Mazzucco G, Varasi M, Doksani Y.
    (2024) Methods Cell Biol. 2024;182:83-94. doi: 10.1016/bs.mcb.2022.11.001. Epub 2022 Dec 13. [38359989 ]

  5. Approaches to Study Wound-Induced Hair Neogenesis (WIHN)
    Dutta A, Saha D, Jamora C.
    (2024) Methods Mol Biol. 2024;2849:31-44. doi: 10.1007/7651_2024_522. [38499917 ]

  6. Leveraging Tissue-Specific Enhancer-Target Gene Regulatory Networks Identifies Enhancer Somatic Mutations That Functionally Impact Lung Cancer
    Hariprakash JM, Salviato E, La Mastra F, Sebestyén E, Tagliaferri I, Silva RS, Lucini F, Farina L, Cinquanta M, Rancati I, Riboni M, Minardi SP, Roz L, Gorini F, Lanzuolo C, Casola S, Ferrari F.
    (2024) Cancer Res. 2024 Jan 2;84(1):133-153. doi: 10.1158/0008-5472.CAN-23-1129. [37855660 ]

  7. Pregnancy After Breast Cancer in Young BRCA Carriers: An International Hospital-Based Cohort Study
    Lambertini M, Blondeaux E, Agostinetto E, Hamy AS, Kim HJ, Di Meglio A, Bernstein Molho R, Hilbers F, Pogoda K, Carrasco E, Punie K, Bajpai J, Ignatiadis M, Moore HCF, Phillips KA, Toss A, Rousset-Jablonski C, Peccatori FA, Renaud T, Ferrari A, Paluch-Shimon S, Fruscio R, Cui W, Wong SM, Vernieri C, Ruddy KJ, Dieci MV, Matikas A, Rozenblit M, Villarreal-Garza C, De Marchis L, Del Mastro L, Puglisi F, Del Pilar Estevez-Diz M, Rodriguez-Wallberg KA, Mrinakova B, Meister S, Livraghi L, Clatot F, Yerushalmi R, De Angelis C, Sánchez-Bayona R, Meattini I, Cichowska-Cwalinska N, Berlière M, Salama M, De Giorgi U, Sonnenblick A, Chiodi C, Lee YJ, Maria C, Azim HA Jr, Boni L, Partridge AH; BRCA BCY Collaboration.
    (2024) JAMA. 2024 Jan 2;331(1):49-59. doi: 10.1001/jama.2023.25463. [38059899 ]

  8. Impaired activation of plasmacytoid dendritic cells via toll-like receptor 7/9 and STING is mediated by melanoma-derived immunosuppressive cytokines and metabolic drift
    Monti M, Ferrari G, Grosso V, Missale F, Bugatti M, Cancila V, Zini S, Segala A, La Via L, Consoli F, Orlandi M, Valerio A, Tripodo C, Rossato M, Vermi W.
    (2024) Front Immunol. 2024 Jan 3;14:1227648. doi: 10.3389/fimmu.2023.1227648. eCollection 2023. [38239354 ]

  9. SnapShot: DNA repair pathways
    Nunomiya A, Szakal B, Branzei D.
    (2024) Mol Cell. 2024 Jan 4;84(1):180-180.e1. doi: 10.1016/j.molcel.2023.11.030. [38181759 ]

  10. SnapShot: Tolerating replication stress
    Szakal B, Giannattasio M, Branzei D.
    (2024) Mol Cell. 2024 Jan 4;84(1):182-182.e1. doi: 10.1016/j.molcel.2023.11.031. [38181760 ]

  11. NTRK2 expression in gastrointestinal stromal tumors with a special emphasis on the clinicopathological and prognostic impacts
    Sasa K, Son R, Oguchi A, Ashizawa K, Hasegawa N, Kubota D, Suehara Y, Takagi T, Okubo T, Akaike K, Sugimoto K, Takahashi M, Sakamoto K, Hashimoto T, Mine S, Fukunaga T, Ishijima M, Hayashi T, Yao T, Murakawa Y, Saito T.
    (2024) Sci Rep. 2024 Jan 8;14(1):768. doi: 10.1038/s41598-024-51211-7. [38191907 ]

  12. EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening
    Cappelletto A, Alfì E, Volf N, Vu TVA, Bortolotti F, Ciucci G, Vodret S, Fantuz M, Perin M, Colliva A, Rozzi G, Rossi M, Ruozi G, Zentilin L, Vuerich R, Borin D, Lapasin R, Piazza S, Chiesa M, Lorizio D, Triboli L, Kumar S, Morello G, Tripodo C, Pinamonti M, Piperno GM, Benvenuti F, Rustighi A, Jo H, Piccolo S, Del Sal G, Carrer A, Giacca M, Zacchigna S.
    (2024) J Exp Clin Cancer Res. 2024 Jan 10;43(1):15. doi: 10.1186/s13046-023-02942-4. [38195652 ]

  13. Unveiling the mechanistic link between extracellular amyloid fibrils, mechano-signaling and YAP activation in cancer
    Farris F, Elhagh A, Vigorito I, Alongi N, Pisati F, Giannattasio M, Casagrande F, Veghini L, Corbo V, Tripodo C, Di Napoli A, Matafora V, Bachi A.
    (2024) Cell Death Dis. 2024 Jan 11;15(1):28. doi: 10.1038/s41419-024-06424-z. [38199984 ]

  14. Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer
    Rospo G, Chilà R, Matafora V, Basso V, Lamba S, Bartolini A, Bachi A, Di Nicolantonio F, Mondino A, Germano G, Bardelli A.
    (2024) Genome Med. 2024 Jan 19;16(1):15. doi: 10.1186/s13073-023-01275-3. [38243308 ]

  15. Optical Modulation of the Blood-Brain Barrier for Glioblastoma Treatment
    Cai Q, Fan H, Li X, Giannotta M, Bachoo R, Qin Z.
    (2024) Bio Protoc. 2024 Jan 20;14(2):e4920. doi: 10.21769/BioProtoc.4920. eCollection 2024 Jan 20. [38268976 ]

  16. Robustness and reproducibility for AI learning in biomedical sciences: RENOIR
    Barberis A, Aerts HJWL, Buffa FM.
    (2024) Sci Rep. 2024 Jan 22;14(1):1933. doi: 10.1038/s41598-024-51381-4. [38253545 ]

  17. Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion
    Pallavi R, Gatti E, Durfort T, Stendardo M, Ravasio R, Leonardi T, Falvo P, Duso BA, Punzi S, Xieraili A, Polazzi A, Verrelli D, Trastulli D, Ronzoni S, Frascolla S, Perticari G, Elgendy M, Varasi M, Colombo E, Giorgio M, Lanfrancone L, Minucci S, Mazzarella L, Pelicci PG.
    (2024) Nat Commun. 2024 Jan 27;15(1):828. doi: 10.1038/s41467-023-44348-y. [38280853 ]

  18. UMG1/CD3ε-bispecific T-cell engager redirects T-cell cytotoxicity against diffuse large B-cell lymphoma
    Caracciolo D, Polerà N, Belmonte B, Conforti F, Signorelli S, Gulino A, Staropoli N, Tuccillo FM, Bonelli P, Juli G, Grillone K, Ascrizzi S, Cirillo M, Migale L, Ballerini A, Pelizon C, Di Martino MT, Tagliaferri P, Riillo C, Tassone P.
    (2024) Br J Haematol. 2024 Feb;204(2):555-560. doi: 10.1111/bjh.19183. Epub 2023 Nov 14. [37963444 ]

  19. Mechanotransduction through membrane tension: It's all about propagation?
    Ghisleni A, Gauthier NC.
    (2024) Curr Opin Cell Biol. 2024 Feb;86:102294. doi: 10.1016/j.ceb.2023.102294. Epub 2023 Dec 14. [38101114 ]

  20. FANCJ DNA helicase is recruited to the replisome by AND-1 to ensure genome stability
    Boavida A, Napolitano LM, Santos D, Cortone G, Jegadesan NK, Onesti S, Branzei D, Pisani FM.
    (2024) EMBO Rep. 2024 Feb;25(2):876-901. doi: 10.1038/s44319-023-00044-y. Epub 2024 Jan 2. [38177925 ]

  21. Scaling the cellular frontier: Mechanobiology, tissue dynamics and function
    Trejo J, Scita G.
    (2024) Curr Opin Cell Biol. 2024 Feb;86:102318. doi: 10.1016/j.ceb.2023.102318. Epub 2024 Jan 11. [38215514 ]

  22. NOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
    Choi HY, Zhu Y, Zhao X, Mehta S, Hernandez JC, Lee JJ, Kou Y, Machida R, Giacca M, Del Sal G, Ray R, Eoh H, Tahara SM, Chen L, Tsukamoto H, Machida K.
    (2024) Exp Mol Med. 2024 Feb;56(2):461-477. doi: 10.1038/s12276-024-01174-6. Epub 2024 Feb 27. [38409448 ]

  23. N2FXm, a method for joint nuclear and cytoplasmic volume measurements, unravels the osmo-mechanical regulation of nuclear volume in mammalian cells
    Pennacchio FA, Poli A, Pramotton FM, Lavore S, Rancati I, Cinquanta M, Vorselen D, Prina E, Romano OM, Ferrari A, Piel M, Cosentino Lagomarsino M, Maiuri P.
    (2024) Nat Commun. 2024 Feb 7;15(1):1070. doi: 10.1038/s41467-024-45168-4. [38326317 ]

  24. The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12
    Mantonico MV, De Leo F, Quilici G, Colley LS, De Marchis F, Crippa M, Mezzapelle R, Schulte T, Zucchelli C, Pastorello C, Carmeno C, Caprioglio F, Ricagno S, Giachin G, Ghitti M, Bianchi ME, Musco G.
    (2024) Nat Commun. 2024 Feb 8;15(1):1201. doi: 10.1038/s41467-024-45505-7. [38331917 ]

  25. Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction
    Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla MK, Abubakar M, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Baten A, Behrens S, Bermisheva M, de Gonzalez AB, Bia?kowska K, Boddicker N, Bodelon C, Bogdanova NV, Bojesen SE, Brantley KD, Brauch H, Brenner H, Camp NJ, Canzian F, Castelao JE, Cessna MH, Chang-Claude J, Chenevix-Trench G, Chung WK; NBCS Collaborators; Colonna SV, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Devilee P, Dörk T, Dunning AM, Eccles DM, Eliassen AH, Engel C, Eriksson M, Evans DG, Fasching PA, Fletcher O, Flyger H, Fritschi L, Gago-Dominguez M, Gentry-Maharaj A, González-Neira A, Guénel P, Hahnen E, Haiman CA, Hamann U, Hartikainen JM, Ho V, Hodge J, Hollestelle A, Honisch E, Hooning MJ, Hoppe R, Hopper JL, Howell S, Howell A; ABCTB Investigators; kConFab Investigators; Jakovchevska S, Jakubowska A, Jernström H, Johnson N, Kaaks R, Khusnutdinova EK, Kitahara CM, Koutros S, Kristensen VN, Lacey JV, Lambrechts D, Lejbkowicz F, Lindblom A, Lush M, Mannermaa A, Mavroudis D, Menon U, Murphy RA, Nevanlinna H, Obi N, Offit K, Park-Simon TW, Patel AV, Peng C, Peterlongo P, Pita G, Plaseska-Karanfilska D, Pylkäs K, Radice P, et al.
    (2024) medRxiv [Preprint]. 2024 Feb 13:2024.02.12.24302043. doi: 10.1101/2024.02.12.24302043. [38410445 ]

  26. Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
    Sogari A, Rovera E, Grasso G, Mariella E, Reilly NM, Lamba S, Mauri G, Durinikova E, Vitiello PP, Lorenzato A, Avolio M, Piumatti E, Bonoldi E, Aquilano MC, Arena S, Sartore-Bianchi A, Siena S, Trusolino L, Donalisio M, Russo M, Di Nicolantonio F, Lembo D, Bardelli A.
    (2024) Cell Rep Med. 2024 Feb 20;5(2):101376. doi: 10.1016/j.xcrm.2023.101376. Epub 2024 Jan 15. [38228147 ]

  27. ZEB1 shapes AML immunological niches, suppressing CD8 T cell activity while fostering Th17 cell expansion
    Bassani B, Simonetti G, Cancila V, Fiorino A, Ciciarello M, Piva A, Khorasani AM, Chiodoni C, Lecis D, Gulino A, Fonzi E, Botti L, Portararo P, Costanza M, Brambilla M, Colombo G, Schwaller J, Tzankov A, Ponzoni M, Ciceri F, Bolli N, Curti A, Tripodo C, Colombo MP, Sangaletti S.
    (2024) Cell Rep. 2024 Feb 27;43(2):113794. doi: 10.1016/j.celrep.2024.113794. Epub 2024 Feb 15. [38363677 ]

  28. Mutational profile of the regenerative process and de novo genome assembly of the planarian Schmidtea polychroa
    Póti Á, Szüts D, Vermezovic J.
    (2024) Nucleic Acids Res. 2024 Feb 28;52(4):1779-1792. doi: 10.1093/nar/gkad1250. [38180823 ]

  29. Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER(+) breast cancer
    Bacci M, Lorito N, Smiriglia A, Subbiani A, Bonechi F, Comito G, Morriset L, El Botty R, Benelli M, López-Velazco JI, Caffarel MM, Urruticoechea A, Sflomos G, Malorni L, Corsini M, Ippolito L, Giannoni E, Meattini I, Matafora V, Havas K, Bachi A, Chiarugi P, Marangoni E, Morandi A.
    (2024) Sci Transl Med. 2024 Feb 28;16(736):eadf9874. doi: 10.1126/scitranslmed.adf9874. Epub 2024 Feb 28. [38416843 ]

  30. Ketone bodies in cell physiology and cancer
    Giuliani G, Longo VD.
    (2024) Am J Physiol Cell Physiol. 2024 Mar 1;326(3):C948-C963. doi: 10.1152/ajpcell.00441.2023. Epub 2024 Jan 8. [38189128 ]

  31. The role of anti-EGFR rechallenge in metastatic colorectal cancer, from available data to future developments: A systematic review
    Ciardiello D, Mauri G, Sartore-Bianchi A, Siena S, Zampino MG, Fazio N, Cervantes A.
    (2024) Cancer Treat Rev. 2024 Mar;124:102683. doi: 10.1016/j.ctrv.2024.102683. Epub 2024 Jan 12. [38237253 ]

  32. Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk
    Barnes DR, Tyrer JP, Dennis J, Leslie G, Bolla MK, Lush M, Aeilts AM, Aittomäki K, Andrieu N, Andrulis IL, Anton-Culver H, Arason A, Arun BK, Balmaña J, Bandera EV, Barkardottir RB, Berger LPV, de Gonzalez AB, Berthet P, Bia?kowska K, Bjørge L, Blanco AM, Blok MJ, Bobolis KA, Bogdanova NV, Brenton JD, Butz H, Buys SS, Caligo MA, Campbell I, Castillo C, Claes KBM; GEMO Study Collaborators; EMBRACE Collaborators; Colonna SV, Cook LS, Daly MB, Dansonka-Mieszkowska A, de la Hoya M, deFazio A, DePersia A, Ding YC, Domchek SM, Dörk T, Einbeigi Z, Engel C, Evans DG, Foretova L, Fortner RT, Fostira F, Foti MC, Friedman E, Frone MN, Ganz PA, Gentry-Maharaj A, Glendon G, Godwin AK, González-Neira A, Greene MH, Gronwald J, Guerrieri-Gonzaga A, Hamann U, Hansen TVO, Harris HR, Hauke J, Heitz F, Hogervorst FBL, Hooning MJ, Hopper JL, Huff CD, Huntsman DG, Imyanitov EN; kConFab Investigators; Izatt L, Jakubowska A, James PA, Janavicius R, John EM, Kar S, Karlan BY, Kennedy CJ, Kiemeney LALM, Konstantopoulou I, Kupryjanczyk J, Laitman Y, Lavie O, Lawrenson K, Lester J, Lesueur F, Lopez-Pleguezuelos C, Mai PL, Manoukian S, May T, McNeish IA, Menon U, Milne RL, Modugno F, Mongiovi JM, Montagna M, Moysich KB, et al.
    (2024) medRxiv [Preprint]. 2024 Mar 4:2024.02.29.24303243. doi: 10.1101/2024.02.29.24303243. [38496424 ]

  33. Spatially-resolved transcriptomics reveal macrophage heterogeneity and prognostic significance in diffuse large B-cell lymphoma
    Liu M, Bertolazzi G, Sridhar S, Lee RX, Jaynes P, Mulder K, Syn N, Hoppe MM, Fan S, Peng Y, Thng J, Chua R, Jayalakshmi, Batumalai Y, De Mel S, Poon L, Chan EHL, Lee J, Hue SS, Chang ST, Chuang SS, Chandy KG, Ye X, Pan-Hammarström Q, Ginhoux F, Chee YL, Ng SB, Tripodo C, Jeyasekharan AD.
    (2024) Nat Commun. 2024 Mar 8;15(1):2113. doi: 10.1038/s41467-024-46220-z. [38459052 ]

  34. Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors
    López L, Morosi LG, La Terza F, Bourdely P, Rospo G, Amadio R, Piperno GM, Russo V, Volponi C, Vodret S, Joshi S, Giannese F, Lazarevic D, Germano G, Stoitzner P, Bardelli A, Dalod M, Pace L, Caronni N, Guermonprez P, Benvenuti F.
    (2024) Nat Commun. 2024 Mar 13;15(1):2280. doi: 10.1038/s41467-024-46685-y. [38480738 ]

  35. Germinal Center Dark Zone harbors ATR-dependent determinants of T-cell exclusion that are also identified in aggressive lymphoma
    Cancila V, Morello G, Bertolazzi G, Chan AS, Bastianello G, Paysan D, Jaynes PW, Schiavoni G, Mattei F, Piconese S, Revuelta MV, Noto F, De Ninno A, Cammarata I, Pagni F, Venkatachalapathy S, Sangaletti S, Di Napoli A, Vacca D, Lonardi S, Lorenzi L, Ferreri AJM, Belmonte B, Varano G, Colombo MP, Bicciato S, Inghirami G, Cerchietti L, Ponzoni M, Zappasodi R, Facchetti F, Foiani M, Casola S, Jeyasekharan AD, Tripodo C.
    (2024) Res Sq [Preprint]. 2024 Mar 18:rs.3.rs-4093618. doi: 10.21203/rs.3.rs-4093618/v1. [38562878 ]

  36. SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA
    Germani S, Van Ho AT, Cherubini A, Varone E, Chernorudskiy A, Renna GM, Fumagalli S, Gobbi M, Lucchetti J, Bolis M, Guarrera L, Craparotta I, Rastelli G, Piccoli G, de Napoli C, Nogara L, Poggio E, Brini M, Cattaneo A, Bachi A, Simmen T, Calì T, Quijano-Roy S, Boncompagni S, Blaauw B, Ferreiro A, Zito E.
    (2024) Cell Rep Med. 2024 Mar 19;5(3):101439. doi: 10.1016/j.xcrm.2024.101439. Epub 2024 Feb 22. [38402623 ]

  37. New role of fat-free mass in cancer risk linked with genetic predisposition
    Harris BHL, Di Giovannantonio M, Zhang P, Harris DA, Lord SR, Allen NE, Maughan TS, Bryant RJ, Harris AL, Bond GL, Buffa FM.
    (2024) Sci Rep. 2024 Mar 27;14(1):7270. doi: 10.1038/s41598-024-54291-7. [38538606 ]

  38. The MET Oncogene: Thirty Years of Insights into Molecular Mechanisms Driving Malignancy
    Crepaldi T, Gallo S, Comoglio PM.
    (2024) Pharmaceuticals (Basel). 2024 Mar 30;17(4):448. doi: 10.3390/ph17040448. [38675409 ]

  39. Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast
    Mirisola MG, Longo VD.
    (2024) Biomed J. 2024 Apr;47(2):100694. doi: 10.1016/j.bj.2023.100694. Epub 2023 Dec 27. [38154617 ]

  40. Cyclic Fasting-Mimicking Diet Plus Bortezomib and Rituximab Is an Effective Treatment for Chronic Lymphocytic Leukemia
    Raucci F, Vernieri C, Di Tano M, Ligorio F, Bla?evitš O, Lazzeri S, Shmahala A, Fragale G, Salvadori G, Varano G, Casola S, Buono R, Visco E, de Braud F, Longo VD.
    (2024) Cancer Res. 2024 Apr 1;84(7):1133-1148. doi: 10.1158/0008-5472.CAN-23-0295. [38241703 ]

  41. Micronucleus is not a potent inducer of the cGAS/STING pathway
    Sato Y, Hayashi MT.
    (2024) Life Sci Alliance. 2024 Feb 2;7(4):e202302424. doi: 10.26508/lsa.202302424. Print 2024 Apr. [38307626 ]

  42. Judith Campisi (1948-2024)
    Wiley CD, Hara E, d'Adda di Fagagna F.
    (2024) Nat Aging. 2024 Apr;4(4):435-436. doi: 10.1038/s43587-024-00603-5. [38486032 ]

  43. Anti-EGFR Rechallenge in Patients With Refractory ctDNA RAS/BRAF wt Metastatic Colorectal Cancer: A Nonrandomized Controlled Trial
    Ciardiello D, Martinelli E, Troiani T, Mauri G, Rossini D, Martini G, Napolitano S, Famiglietti V, Del Tufo S, Masi G, Santini D, Avallone A, Pietrantonio F, Lonardi S, Di Maio M, Zampino MG, Fazio N, Bardelli A, Siena S, Cremolini C, Sartore-Bianchi A, Ciardiello F.
    (2024) JAMA Netw Open. 2024 Apr 1;7(4):e245635. doi: 10.1001/jamanetworkopen.2024.5635. [38592721 ]

  44. Orthogonal analysis of mitochondrial function in Parkinson's disease patients
    Barnhoorn S, Milanese C, Li T, Dons L, Ghazvini M, Sette M, Farina S, Sproviero D, Payan-Gomez C, Mastroberardino PG.
    (2024) Cell Death Dis. 2024 Apr 3;15(4):243. doi: 10.1038/s41419-024-06617-6. [38570521 ]

  45. Real-World Outcomes of Trastuzumab Deruxtecan in Patients With HER2+ Metastatic Breast Cancer: The DE-REAL Study
    Botticelli A, Caputo R, Scagnoli S, Pisegna S, De Laurentiis M, Curigliano G, Lambertini M, Pantano F, Palazzo A, Paris I, Vernieri C, Tedesco B, Giampaglia M, Palleschi M, Ballatore Z, Alesini D, D'Auria G, Fabbri A, Rossi L, Verrazzo A, Scafetta R, Marinelli D, Sposetti C, Barberi V, Strigari L, Marchetti P, Santini D, Fabi A.
    (2024) Oncologist. 2024 Apr 4;29(4):303-310. doi: 10.1093/oncolo/oyad308. [37995313 ]

  46. Mapping functional to morphological variation reveals the basis of regional extracellular matrix subversion and nerve invasion in pancreatic cancer
    Di Chiaro P, Nacci L, Arco F, Brandini S, Polletti S, Palamidessi A, Donati B, Soriani C, Gualdrini F, Frigè G, Mazzarella L, Ciarrocchi A, Zerbi A, Spaggiari P, Scita G, Rodighiero S, Barozzi I, Diaferia GR, Natoli G.
    (2024) Cancer Cell. 2024 Apr 8;42(4):662-681.e10. doi: 10.1016/j.ccell.2024.02.017. Epub 2024 Mar 21. [38518775 ]

  47. Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition
    Ribeiro CF, Rodrigues S, Bastos DC, Fanelli GN, Pakula H, Foiani M, Zadra G, Loda M.
    (2024) Sci Signal. 2024 Apr 9;17(831):eadh1922. doi: 10.1126/scisignal.adh1922. Epub 2024 Apr 9. [38593154 ]

  48. Morphomics via next-generation electron microscopy
    Son R, Yamazawa K, Oguchi A, Suga M, Tamura M, Yanagita M, Murakawa Y, Kume S.
    (2024) J Mol Cell Biol. 2024 Apr 10;15(12):mjad081. doi: 10.1093/jmcb/mjad081. [38148118 ]

  49. Cross-contamination of CRISPR guides and other unrelated nucleotide sequences among commercial oligonucleotides
    Arakawa H, Miura H, Quadros RM, Ohtsuka M, Gurumurthy CB.
    (2024) Nucleic Acids Res. 2024 Apr 12;52(6):3137-3145. doi: 10.1093/nar/gkae068. [38324466 ]

  50. A mean-field theory for predicting single polymer collapse induced by neutral crowders
    Chaboche Q, Campos-Villalobos G, Giunta G, Dijkstra M, Cosentino Lagomarsino M, Scolari VF.
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  107. Prediction of homologous recombination deficiency identifies colorectal tumors sensitive to PARP inhibition
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  108. How to Test HER2 for Predicting Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer? Evidence From the Secondary Analysis of Biomarkers of CALGB/SWOG 80405
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  109. Biallelic GGGCC repeat expansion leading to NAXE-related mitochondrial encephalopathy
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  111. Epigenetic regulation by polycomb repressive complex 1 promotes cerebral cavernous malformations
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  112. Hepatoid thymic carcinoma in a polycythemia vera patient treated with ropeginterferon Alfa-2b: Clinical, histopathological and molecular correlates
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  113. A Comparative Study of Methyl-BEAMing and Droplet Digital PCR for MGMT Gene Promoter Hypermethylation Detection
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  114. USP1 deubiquitinates PARP1 to regulate its trapping and PARylation activity
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  115. Prognostic Relevance of Copy Number Losses in Ovarian Cancer
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  116. Identification of HER2-positive breast cancer molecular subtypes with potential clinical implications in the ALTTO clinical trial
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  117. Morphometric Similarity Patterning of Amyloid-β and Tau Proteins Correlates with Transcriptomics in the Alzheimer's Disease Continuum
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  118. Ongoing Clinical Trials and Future Research Scenarios of Circulating Tumor DNA for the Treatment of Metastatic Colorectal Cancer
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  119. Biomimetic Approach of Brain Vasculature Rapidly Characterizes Inter- and Intra-Patient Migratory Diversity of Glioblastoma
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  120. Immune and gene-expression profiling in estrogen receptor low and negative early breast cancer
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  121. Cyclophilin D plays a critical role in the survival of senescent cells
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  123. Interleukin-6 transcripts up-regulation in lymph nodes from unicentric and multicentric Castleman disease
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  124. HRK downregulation and augmented BCL-xL binding to BAK confer apoptotic protection to therapy-induced senescent melanoma cells
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  125. Is tumour sequencing effective for the identification of germline BRCA1/2 pathogenic variant carriers?
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  126. Clinicopathological characterisation of MTAP alterations in gastrointestinal cancers
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  127. dl-Limonene as an Alternative Sustainable Solvent to Xylenes for the Industrial Preparation of Release Formulations
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  128. Spatially Precise and Minimally Invasive Delivery of Peptides to the Spinal Cord for Behavior Modulation
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  129. SP140 represses specific loci by recruiting polycomb repressive complex 2 and NuRD complex
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  130. A multiparametric screen uncovers FDA-approved small molecules that potentiate the nuclear mechano-dysfunctions in ATR-defective cells
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  131. Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
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