IFOM

Post-doctoral Research Scientist | Leuzzi’s laboratory

2026/05 | Milan

IFOM is an internationally recognized non-profit cancer research institute supported by the Italian Association for Cancer Research (AIRC) based in Milan within a highly dynamic urban environment.

IFOM’s continuous success is ensured by the recruitment of highly-competitive undergraduate, graduate and post-graduate researchers worldwide, with over 24 countries currently represented in IFOM.

IFOM labs are hosted within a research campus shared with the European Institute of Oncology and the Italian Institute of Technology.

IFOM is committed to creating a safe and inclusive work environment, based on mutual respect and on the enhancement of diversity, offering equal job opportunities to all qualified candidates.

We are recruiting for out Insitute a Post-doctoral Research Scientist

About the position

We are seeking a highly motivated, independent postdoctoral researcher to join our team.

The selected candidate will be responsable for:

  • Design and execute CRISPR-knockout (CRISPR-KO) and CRISPR-mediated base editing screens to investigate novel targets and biomarkers in cancer immunity.
  • Perform experimental approaches to study DNA damage response (DDR) pathways and their role in tumor-immune interactions.
  • Generate, analyze, and interpret data to drive discovery and publications.
  • Drafting scientific manuscripts and contributing to the overall preparation of research for publication.
  • Collaborate with other laboratories.
  • Attend national and international meetings to present research findings and learn the latest advances in the field.

Department overview

The position is in the Leuzzi Lab

Our research: Cancer cells are not invisible to the immune system, but many find ways to hide. Some exploit DNA damage response (DDR) pathways to suppress immune activation, while others accumulate mutations that reshape their interaction with immune cells. Understanding these mechanisms is critical for developing new therapies that enhance the immune system’s ability to target tumors.

The Leuzzi Lab investigates how DNA repair mechanisms and genome instability shape tumor-immune interactions, aiming to uncover novel strategies to enhance cancer immunotherapy. Our lab employs an interdisciplinary approach, combining CRISPR-based genome engineering, high-throughput functional genomics, multi-omics analyses, and in vivo models to dissect these critical processes.

Profile Description

We are seeking a higly motivated, independent postdoctoral researcher to join our team. The successful candidate will thrive in our collaborative, international research environment, which offers access to cutting-edge technologies and strong institutional support. This position provides an exceptional opportunity to develop innovative projects at the intersection of cancer biology and tumor immunology, gains hands-on experience in high-throughput functional genomics, while advancing your scientific career in a highly supportive and stimulating setting.

Language skills

Proficiency in English for speaking and writing - English is the working language at the Institute.

Required skills

  • Extensive knowledge in DNA repair or CRISPR-based screening approaches;
  • Self-motivation and a curiosity-driven mindset;
  • Strong publication record, including at least one publication in the last year with the applicant as principal author;
  • Great communication skills and strong motivation to work in a collaborative and constructive lab environment.

Educational experience

PhD in Molecular biology, Cancer biology, Genetics or related area.

What we offer

  • International work environment; Flextime; Guest house inside the Campus
  • Agreements with discounts for Gym, Pharmacy, Psychology service and various shops around IFOM area; Bar and canteen inside the campus & lunch benefit; Company Nursery
  • Continuous support to candidates and their families (including homing, schooling, registration to the national health system, work permit etc.) thanks to the activities of the Welcome office
  • Medical Service; Laptop; CAF service - tax declaration

Type of Contract

Annual renewable fellowship (post-doc).

The candidate will be offered a competitive salary, commensurate with skills and working experience.

Location

Milan – Scalo di Porta Romana area

Contacts

Candidates should send:

  • CV
  • Cover letter describing your previous research, your research interests and motivation for joining our team
  • Contact details for two/three references to: giuseppe.leuzzi@ifom.eu

Consideration of applications will begin as they are received and will continue until the position is filled.

last update: 15/05/26
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