IFOM Publications Dana Branzei
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Publications Dana Branzei

  1. Psakhye I, Kawasumi R, Abe T, Hirota K, Branzei D.
    PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion.
    Nat Struct Mol Biol. 2023 Aug 17. doi: 10.1038/s41594-023-01064-x. Online ahead of print. PMID: 37592094
  2. Joseph CR, Dusi S, Giannattasio M, Branzei D.
    Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase.
    Nat Commun. 2022 May 5;13(1):2480. doi: 10.1038/s41467-022-30215-9. PMID: 35513396; PMCID: PMC9072374.
  3. Dolce V, Dusi S, Giannattasio M, Joseph CR, Fumasoni M, Branzei D.
    Parental histone deposition on the replicated strands promotes error-free DNA damage tolerance and regulates drug resistance
    Genes Dev. 2022 Feb 1;36(3-4):167-179. doi: 10.1101/gad.349207.121. Epub 2022 Feb 3. PMID: 35115379; PMCID: PMC8887126.
  4. Kannan A, Cuartas J, Gangwani P, Branzei D, Gangwani L.
    Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4
    Brain. 2022 Sep 14;145(9):3072-3094. doi: 10.1093/brain/awab464. PMID: 35045161; PMCID: PMC9536298.
  5. Humphreys IR, Pei J, Baek M, Krishnakumar A, Anishchenko I, Ovchinnikov S, Zhang J, Ness TJ, Banjade S, Bagde SR, Stancheva VG, Li XH, Liu K, Zheng Z, Barrero DJ, Roy U, Kuper J, Fernández IS, Szakal B, Branzei D, Rizo J, Kisker C, Greene EC, Biggins S, Keeney S, Miller EA, Fromme JC, Hendrickson TL, Cong Q, Baker D.
    Computed structures of core eukaryotic protein complexes.
    Science. 2021 Dec 10;374(6573):eabm4805. doi: 10.1126/science.abm4805. Epub 2021 Dec 10. PMID: 34762488; PMCID: PMC7612107.
  6. Kawasumi R, Abe T, Psakhye I, Miyata K, Hirota K, Branzei D.
    Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release.
    Genes Dev. 2021 Oct 1;35(19-20):1368-1382. doi:10.1101/gad.348581.121. Epub 2021 Sep 9. PMID: 34503989; PMCID: PMC8494208.
  7. Psakhye I, Branzei D.
    SMC complexes are guarded by the SUMO protease Ulp2 against SUMO-chain-mediated turnover.
    Cell Rep. 2021 Aug 3;36(5):109485. doi:10.1016/j.celrep.2021.109485. PMID: 34348159.
  8. Branzei D, Szakal B.
    DNA helicases in homologous recombination repair
    Curr Opin Genet Dev. 2021 Dec;71:27-33. doi: 10.1016/j.gde.2021.06.009. Epub 2021 Jul 14. PMID: 34271541.
  9. Jegadesan NK, Branzei D.
    DDX11 loss causes replication stress and pharmacologically exploitable DNA repair defects
    Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):e2024258118. doi: 10.1073/pnas.2024258118. PMID: 33879618; PMCID: PMC8092582.
  10. Agashe S, Joseph CR, Reyes TAC, Menolfi D, Giannattasio M, Waizenegger A, Szakal B, Branzei D.
    Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites.
    Nat Commun. 2021 Apr 8;12(1):2111. doi: 10.1038/s41467-021-22217-w. PMID: 33833229; PMCID: PMC8032827.
  11. Waizenegger A, Urulangodi M, Lehmann CP, Reyes TAC, Saugar I, Tercero JA, Szakal B, Branzei D.
    Mus81-Mms4 endonuclease is an Esc2-STUbL-Cullin8 mitotic substrate impacting on genome integrity.
    Nat Commun. 2020 Nov 12;11(1):5746. doi: 10.1038/s41467-020-19503-4. PMID: 33184279; PMCID: PMC7665200.
  12. Lerner LK, Holzer S, Kilkenny ML, Šviković S, Murat P, Schiavone D, Eldridge CB, Bittleston A, Maman JD, Branzei D, Stott K, Pellegrini L, Sale JE.
    Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
    EMBO J. 2020 Sep 15;39(18):e104185. doi: 10.15252/embj.2019104185. Epub 2020 Jul 23. PMID: 32705708; PMCID: PMC7506991.
  13. Lehmann CP, Jiménez-Martín A, Branzei D, Tercero JA.
    Prevention of unwanted recombination at damaged replication forks.
    Curr Genet. 2020. Dec;66(6):1045-1051. doi: 10.1007/s00294-020-01095-7. Epub 2020 Jul 15. PMID: 32671464; PMCID: PMC7599154.
  14. Jiménez-Martín A, Saugar I, Joseph CR, Mayer A, Lehmann CP, Szakal B, Branzei D, Tercero JA.
    The Mgs1/WRNIP1 ATPase is required to prevent a recombination salvage pathway at damaged replication forks.
    Sci Adv. 2020 Apr 8;6(15):eaaz3327. doi: 10.1126/sciadv.aaz3327. PMID: 32285001; PMCID:PMC7141828.
  15. Rossi F, Helbling-Leclerc A, Kawasumi R, Jegadesan NK, Xu X, Devulder P, Abe T, Takata M, Xu D, Rosselli F, Branzei D.
    SMC5/6 acts jointly with Fanconi anemia factors to support DNA repair and genome stability.
    EMBO Rep. 2020 Feb 5;21(2):e48222. doi: 10.15252/embr.201948222. Epub 2019 Dec 23. PMID: 31867888; PMCID: PMC7001510.
  16. Psakhye I, Castellucci F, Branzei D.
    SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation.
    Mol Cell. 2019 Nov 21;76(4):632-645.e6. doi: 10.1016/j.molcel.2019.08.003. Epub 2019 Sep 10. PMID:31519521; PMCID: PMC6891891.
  17. Menolfi D, Branzei D.
    Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo.
    Methods Mol Biol. 2019;2004:3-16. doi:10.1007/978-1-4939-9520-2_1. PMID: 31147905.
  18. Giannattasio M, Branzei D.
    DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae.
    Genes (Basel). 2019 Feb 21;10(2):167. doi: 10.3390/genes10020167. PMID: 30795600; PMCID: PMC6409922.
  19. Gallo D, Kim T, Szakal B, Saayman X, Narula A, Park Y, Branzei D, Zhang Z,Brown GW.
    Rad5 Recruits Error-Prone DNA Polymerases for Mutagenic Repair of ssDNA Gaps on Undamaged Templates.
    Mol Cell. 2019 Mar 7;73(5):900-914.e9. doi:10.1016/j.molcel.2019.01.001. Epub 2019 Feb 4. PMID: 30733119.
  20. Abe T, Branzei D, Hirota K.
    DNA Damage Tolerance Mechanisms Revealed from the Analysis of Immunoglobulin V Gene Diversification in Avian DT40 Cells.
    Genes (Basel). 2018 Dec 7;9(12):614. doi: 10.3390/genes9120614. PMID: 30544644; PMCID: PMC6316486.
  21. Srivatsan A, Li BZ, Szakal B, Branzei D, Putnam CD, Kolodner RD.
    The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects.
    Nat Commun. 2018 Sep 11;9(1):3680.doi:10.1038/s41467-018-06131-2.PMID:30206225; PMCID: PMC6134005.
  22. Litwin I, Bakowski T, Szakal B, Pilarczyk E, Maciaszczyk-Dziubinska E, Branzei D, Wysocki R.
    Error-free DNA damage tolerance pathway is facilitated by the Irc5 translocase through cohesin.
    EMBO J. 2018 Sep 14;37(18):e98732. doi:10.15252/embj.201798732. Epub 2018 Aug 14. PMID: 30111537; PMCID: PMC6138436.
  23. Abe T, Kawasumi R, Giannattasio M, Dusi S, Yoshimoto Y, Miyata K, Umemura K, Hirota K, Branzei D.
    AND-1 fork protection function prevents fork resection and is essential for proliferation.
    Nat Commun. 2018 Aug 6;9(1):3091. doi:10.1038/s41467-018-05586-7. PMID: 30082684; PMCID: PMC6079002.
  24. Abe T, Ooka M, Kawasumi R, Miyata K, Takata M, Hirota K, Branzei D.
    Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites.
    Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8412-8417. doi: 10.1073/pnas.1803110115. Epub 2018 Jul 30. PMID: 30061412; PMCID: PMC6099846.
  25. Iacovella MG, Bremang M, Basha O, Giacò L, Carotenuto W, Golfieri C, Szakal B, Dal Maschio M, Infantino V, Beznoussenko GV, Joseph CR, Visintin C, Mironov AA, Visintin R, Branzei D, Ferreira-Cerca S, Yeger-Lotem E, De Wulf P.
    Integrating Rio1 activities discloses its nutrient-activated network in Saccharomyces cerevisiae.
    Nucleic Acids Res. 2018 Sep 6;46(15):7586-7611. doi:10.1093/nar/gky618. PMID: 30011030; PMCID: PMC6125641.
  26. Kannan A, Bhatia K, Branzei D, Gangwani L.
    Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy.
    Nucleic Acids Res. 2018 Sep 19;46(16):8326-8346.doi:10.1093/nar/gky641.PMID: 30010942; PMCID: PMC6144794.
  27. Nakazato A, Kajita K, Ooka M, Akagawa R, Abe T, Takeda S, Branzei D, Hirota K.
    SPARTAN promotes genetic diversification of the immunoglobulin-variable gene locus in avian DT40 cells.
    DNA Repair (Amst). 2018 Aug;68:50-57. doi:10.1016/j.dnarep.2018.06.003. Epub 2018 Jun 18. PMID: 29935364.
  28. Bharti SK, Sommers JA, Awate S, Bellani MA, Khan I, Bradley L, King GA, Seol Y, Vidhyasagar V, Wu Y, Abe T, Kobayashi K, Shin-Ya K, Kitao H, Wold MS, Branzei D, Neuman KC, Brosh RM Jr.
    A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair.
    Nucleic Acids Res. 2018 Jul 6;46(12):6238-6256. doi: 10.1093/nar/gky403. PMID:29788478; PMCID: PMC6159516.
  29. SIRFing the replication fork: Assessing protein interactions with nascent DNA.
    Branzei D, Giannattasio M.
    J Cell Biol. 2018 Apr 2;217(4):1177-1179. doi:10.1083/jcb.201802083. Epub 2018 Mar 1. PMID: 29496736; PMCID: PMC5881512.
  30. Kawasumi R, Abe T, Arakawa H, Garre M, Hirota K, Branzei D.
    ESCO1/2's roles in chromosome structure and interphase chromatin organization.
    Genes Dev. 2017 Nov 1;31(21):2136-2150. doi: 10.1101/gad.306084.117. Epub 2017 Dec 1. PMID: 29196537; PMCID: PMC5749162.
  31. Branzei D, Szakal B.
    Building up and breaking down: mechanisms controlling recombination during replication.
    Crit Rev Biochem Mol Biol. 2017 Aug;52(4):381-394. doi: 10.1080/10409238.2017.1304355. Epub 2017 Mar 22. PMID: 28325102.
  32. Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.
    Erratum to 'Exploring and exploiting the systemic effects of deregulated replication licensing [Seminars in Cancer Biology 37-38C, (2016) 3-15].
    Semin Cancer Biol. 2017 Apr;43:180. doi: 10.1016/j.semcancer.2017.02.002. Epub 2017 Feb 21. Erratum for: Semin Cancer Biol. 2016 Jun;37-38:3-15. PMID: 28254408.
  33. Giannattasio M, Branzei D.
    S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.
    Cell Mol Life Sci. 2017 Jul;74(13):2361-2380. doi: 10.1007/s00018-017-2474-4. Epub 2017 Feb 20. PMID: 28220209; PMCID: PMC5487892.
  34. Branzei D, Ciliberto A.
    Not all roads lead to Cdk1.
    Cell Cycle. 2017 Mar 4;16(5):395-396. doi: 10.1080/15384101.2016.1274585. Epub 2017 Feb 6. PMID:28165884; PMCID: PMC5351925.
  35. Dana Branzei.
    Cell scientist to watch – Dana Branzei
    J Cell Sci 1 October 2017; 130 (19): 3193–3195. doi: https://doi.org/10.1242/jcs.209510>
  36. Hoppe T, Branzei D.
    Stefan Jentsch (1955-2016)-Maestro of the ubiquitin family.
    EMBO J. 2017 Jan 4;36(1):1-2. doi: 10.15252/embj.201696176. Epub 2016 Dec 14. PMID: 27974363; PMCID: PMC5210126.
  37. Sebesta M, Urulangodi M, Stefanovie B, Szakal B, Pacesa M, Lisby M, Branzei D, Krejci L.
    Esc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains.
    Nucleic Acids Res. 2017 Jan 9;45(1):215-230. doi:10.1093/nar/gkw882. Epub 2016 Sep 30. PMID: 27694623; PMCID: PMC5224511.
  38. Abe T, Kawasumi R, Arakawa H, Hori T, Shirahige K, Losada A, Fukagawa T, Branzei D.
    Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion.
    Oncotarget. 2016 Oct 18;7(42):67934-67947. doi: 10.18632/oncotarget.11982. PMID: 27636994; PMCID:PMC5356530.
  39. Bonner JN, Choi K, Xue X, Torres NP, Szakal B, Wei L, Wan B, Arter M, Matos J, Sung P, Brown GW, Branzei D, Zhao X.
    Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates
    Cell Rep. 2016 Jul 12;16(2):368-378. doi: 10.1016/j.celrep.2016.06.015. Epub 2016 Jun 30. PMID: 27373152; PMCID: PMC5051638.
  40. Branzei D.
    DNA damage tolerance branches out toward sister chromatid cohesion.
    Mol Cell Oncol. 2015 May 7;3(1):e1035478. doi:10.1080/23723556.2015.1035478. PMID: 27308553; PMCID: PMC4845193.
  41. Branzei D, Szakal B.
    DNA damage tolerance by recombination: Molecular pathways and DNA structures.
    DNA Repair (Amst). 2016 Aug;44:68-75. doi:10.1016/j.dnarep.2016.05.008. Epub 2016 May 16. PMID: 27236213; PMCID: PMC4962778.
  42. Branzei D, Psakhye I.
    DNA damage tolerance.
    Curr Opin Cell Biol. 2016 Jun;40:137-144. doi: 10.1016/j.ceb.2016.03.015. Epub 2016 Apr 6. PMID: 27060551.
  43. Branzei D, Szakal B.
    Priming for tolerance and cohesion at replication forks.
    Nucleus. 2016;7(1):8-12. doi: 10.1080/19491034.2016.1149663. Epub 2016 Feb 18. Erratum in: doi: 10.1016/j.molcel.2014.12.038. PMID: 26889705; PMCID: PMC4916891.
  44. Böhm S, Szakal B, Herken BW, Sullivan MR, Mihalevic MJ, Kabbinavar FF, Branzei D, Clark NL, Bernstein KA.
    The Budding Yeast Ubiquitin Protease Ubp7 Is a Novel Component Involved in S Phase Progression.
    J Biol Chem. 2016 Feb 26;291(9):4442-52. doi: 10.1074/jbc.M115.671057. Epub 2016 Jan 6. PMID:26740628; PMCID: PMC4813472.
  45. Petrakis TG, Komseli ES, Papaioannou M, Vougas K, Polyzos A, Myrianthopoulos V, Mikros E, Trougakos IP, Thanos D, Branzei D, Townsend P, Gorgoulis VG.
    Exploring and exploiting the systemic effects of deregulated replication licensing.
    Semin Cancer Biol. 2016 Jun;37-38:3-15. doi:10.1016/j.semcancer.2015.12.002. Epub 2015 Dec 17. Erratum in: Semin Cancer Biol. 2017 Apr;43:180. PMID: 26707000.
  46. Menolfi D, Delamarre A, Lengronne A, Pasero P, Branzei D.
    Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.
    Mol Cell. 2015 Dec 17;60(6):835-46. doi:10.1016/j.molcel.2015.10.023. Epub 2015 Nov 19. PMID: 26698660; PMCID:PMC4691243.
  47. Branzei D, Menolfi D.
    G2/M chromosome transactions essentially relying on Smc5/6.
    Cell Cycle. 2016;15(5):611-2. doi: 10.1080/15384101.2015.1131525. Epub 2015 Dec 22. PMID: 26694861; PMCID: PMC4845932.
  48. Urulangodi M, Szakal B, Branzei D.
    SUMO-mediated global and local control of recombination.
    Cell Cycle. 2016;15(2):160-1. doi: 10.1080/15384101.2015.1118918. Epub 2015 Nov 20. PMID: 26587752; PMCID: PMC4825823.
  49. Urulangodi M, Sebesta M, Menolfi D, Szakal B, Sollier J, Sisakova A, Krejci L, Branzei D.
    Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication.
    Genes Dev. 2015 Oct 1;29(19):2067-80. doi: 10.1101/gad.265629.115. PMID: 26443850; PMCID:PMC4604347.
  50. Hang LE, Peng J, Tan W, Szakal B, Menolfi D, Sheng Z, Lobachev K, Branzei D, Feng W, Zhao X.
    Rtt107 Is a Multi-functional Scaffold Supporting Replication. Progression with Partner SUMO and Ubiquitin Ligases.
    Mol Cell. 2015 Oct 15;60(2):268-79. doi: 10.1016/j.molcel.2015.08.023. Epub 2015 Oct 1. PMID:26439300; PMCID: PMC4609303.
  51. Xue X, Choi K, Bonner JN, Szakal B, Chen YH, Papusha A, Saro D, Niu H, Ira G, Branzei D, Sung P, Zhao X.
    Selective modulation of the functions of a conserved DNA motor by a histone fold complex.
    Genes Dev. 2015 May 15;29(10):1000-5. doi: 10.1101/gad.259143.115. Epub 2015 May 8. PMID: 25956905; PMCID: PMC4441048.
  52. Branzei D.
    DNA damage tolerance branches out toward sister chromatid cohesion.
    Mol Cell Oncol. 2015 May 7;3(1):e1035478. doi:10.1080/23723556.2015.1035478. PMID: 27308553; PMCID: PMC4845193.
  53. Choi K, Batke S, Szakal B, Lowther J, Hao F, Sarangi P, Branzei D, Ulrich HD, Zhao X.
    Concerted and differential actions of two enzymatic domains underlie Rad5 contributions to DNA damage tolerance.
    Nucleic Acids Res. 2015 Mar 11;43(5):2666-77. doi: 10.1093/nar/gkv004. Epub 2015 Feb 17. PMID: 25690888; PMCID: PMC4357696.
  54. Fumasoni M, Zwicky K, Vanoli F, Lopes M, Branzei D.
    Error-free DNA damage tolerance and sister chromatid proximity during DNA replication rely on the Polα/Primase/Ctf4 Complex.
    Mol Cell. 2015 Mar 5;57(5):812-823. doi:10.1016/j.molcel.2014.12.038. Epub 2015 Feb 5. PMID: 25661486; PMCID:MC4352764.
  55. Abe T, Branzei D.
    High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.
    DNA Repair (Amst). 2014 Oct;22:153-64. doi: 10.1016/j.dnarep.2014.08.003. Epub 2014 Sep 16. PMID: 25218467; PMCID: PMC4194320.
  56. Giannattasio M, Zwicky K, Follonier C, Foiani M, Lopes M, Branzei D.
    Visualization of recombination-mediated damage bypass by template switching.
    Nat Struct Mol Biol. 2014 Oct;21(10):884-92. doi: 10.1038/nsmb.2888. Epub 2014 Sep 7. PMID: 25195051; PMCID: PMC4189914.
  57. Kramarz K, Litwin I, Cal-Bąkowska M, Szakal B, Branzei D, Wysocki R, Dziadkowiec D.
    Swi2/Snf2-like protein Uls1 functions in the Sgs1-dependent pathway of maintenance of rDNA stability and alleviation of replication stress.
    DNA Repair (Amst). 2014 Sep;21:24-35. doi: 10.1016/j.dnarep.2014.05.008. Epub 2014 Jun 19. PMID: 25091157.
  58. Gritenaite D, Princz LN, Szakal B, Bantele SC, Wendeler L, Schilbach S, Habermann BH, Matos J, Lisby M, Branzei D, Pfander B.
    A cell cycle-regulated Slx4-Dpb11 complex promotes the resolution of DNA repair intermediates linked to stalled replication.
    Genes Dev. 2014 Jul 15;28(14):1604-19. doi:10.1101/gad.240515.114. PMID: 25030699; PMCID: PMC4102767.
  59. Gonzalez-Huici V, Szakal B, Urulangodi M, Psakhye I, Castellucci F, Menolfi D, Rajakumara E, Fumasoni M, Bermejo R, Jentsch S, Branzei D.
    DNA bending facilitates the error-free DNA damage tolerance pathway and upholds genome integrity.
    EMBO J. 2014 Feb 18;33(4):327-40. doi: 10.1002/embj.201387425. Epub 2014 Jan 28. PMID: 24473148; PMCID: PMC3983681.
  60. Chen YH, Szakal B, Castellucci F, Branzei D, Zhao X.
    DNA damage checkpoint and recombinational repair differentially affect the replication stress tolerance of Smc6 mutants.
    Mol Biol Cell. 2013 Aug;24(15):2431-41. doi:10.1091/mbc.E12-11-0836. Epub 2013 Jun 19. PMID: 23783034; PMCID: PMC3727935.
  61. Szakal B, Branzei D.
    Premature Cdk1/Cdc5/Mus81 pathway activation induces aberrant replication and deleterious crossover.
    EMBO J. 2013 Apr 17;32(8):1155-67. doi: 10.1038/emboj.2013.67. Epub 2013 Mar 26. PMID: 23531881; PMCID: PMC3630363.
  62. Yong-Gonzales V, Hang LE, Castellucci F, Branzei D, Zhao X.
    The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.
    PLoS One. 2012;7(12):e51540. doi:10.1371/journal.pone.0051540. Epub 2012 Dec 20. PMID: 23284708; PMCID:PMC3527468.
  63. Karras GI, Fumasoni M, Sienski G, Vanoli F, Branzei D, Jentsch S.
    Noncanonical role of the 9-1-1 clamp in the error-free DNA damage tolerance pathway.
    Mol Cell. 2013 Feb 7;49(3):536-46. doi: 10.1016/j.molcel.2012.11.016. Epub 2012 Dec 20. PMID: 23260657.
  64. Era S, Abe T, Arakawa H, Kobayashi S, Szakal B, Yoshikawa Y, Motegi A,Takeda S, Branzei D.
    The SUMO protease SENP1 is required for cohesion maintenance and mitotic arrest following spindle poison treatment.
    Biochem Biophys Res Commun. 2012 Sep 28;426(3):310-6. doi: 10.1016/j.bbrc.2012.08.066. Epub 2012 Aug 27. PMID: 22943854.
  65. Daee DL, Ferrari E, Longerich S, Zheng XF, Xue X, Branzei D, Sung P, Myung K.
    Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1.
    J Biol Chem. 2012 Aug 3;287(32):26563-75. doi:10.1074/jbc.M112.369918. Epub 2012 Jun 12. PMID: 22696213; PMCID: PMC3410997.
  66. Bustard DE, Menolfi D, Jeppsson K, Ball LG, Dewey SC, Shirahige K, Sjögren C, Branzei D, Cobb JA.
    During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks.
    J Biol Chem. 2012 Mar 30;287(14):11374-83. doi: 10.1074/jbc.M111.336263. Epub 2012 Feb 2. PMID: 22303010; PMCID: PMC3322872.
  67. Branzei D.
    The three SMC sisters.
    Nat Rev Mol Cell Biol. 2011 Jun;12(6):343. doi: 10.1038/nrm3125. Epub 2011 May 18. PMID: 21587291.
  68. Branzei D.
    Ubiquitin family modifications and template switching.
    FEBS Lett. 2011 Sep 16;585(18):2810-7. doi: 10.1016/j.febslet.2011.04.053. Epub 2011 Apr 29. PMID: 21539841.
  69. Vanoli F, Fumasoni M, Szakal B, Maloisel L, Branzei D.
    Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch.
    PLoS Genet. 2010 Nov 11;6(11):e1001205. doi:10.1371/journal.pgen.1001205. PMID: 21085632; PMCID: PMC2978687.
  70. Choi K, Szakal B, Chen YH, Branzei D, Zhao X.
    The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiae.
    Mol Biol Cell. 2010 Jul 1;21(13):2306-14. doi:10.1091/mbc.e10-01-0050. Epub 2010 May 5. PMID: 20444977; PMCID: PMC2893993.
  71. Branzei D, Foiani M.
    Maintaining genome stability at the replication fork.
    Nat Rev Mol Cell Biol. 2010 Mar;11(3):208-19. doi: 10.1038/nrm2852. PMID: 20177396.
  72. Branzei D, Foiani M.
    Leaping forks at inverted repeats.
    Genes Dev. 2010 Jan 1;24(1):5-9. doi: 10.1101/gad.1884810. PMID: 20047996; PMCID: PMC2802191.
  73. Chen YH, Choi K, Szakal B, Arenz J, Duan X, Ye H, Branzei D, Zhao X.
    Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair.
    Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21252-7. doi: 10.1073/pnas.0908258106. Epub 2009 Dec 7. PMID: 19995966; PMCID: PMC2795505.
  74. Branzei D, Foiani M.
    The checkpoint response to replication stress.
    DNA Repair (Amst). 2009 Sep 2;8(9):1038-46. doi: 10.1016/j.dnarep.2009.04.014. Epub 2009 May 23. PMID: 19482564.
  75. Bernstein KA, Shor E, Sunjevaric I, Fumasoni M, Burgess RC, Foiani M, Branzei D, Rothstein R.
    Sgs1 function in the repair of DNA replicationintermediates is separable from its role in homologous recombinational repair.
    EMBO J. 2009 Apr 8;28(7):915-25. doi: 10.1038/emboj.2009.28. Epub 2009 Feb 12. PMID: 19214189; PMCID: PMC2670856.
  76. Sollier J, Driscoll R, Castellucci F, Foiani M, Jackson SP, Branzei D.
    The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair.
    Mol Biol Cell. 2009 Mar;20(6):1671-82. doi:10.1091/mbc.e08-08-0875. Epub 2009 Jan 21. PMID: 19158389; PMCID: PMC2655255.
  77. Branzei D, Vanoli F, Foiani M.
    SUMOylation regulates Rad18-mediated template switch.
    Nature. 2008 Dec 18;456(7224):915-20. doi: 10.1038/nature07587. PMID: 19092928.
  78. Bermejo R, Branzei D, Foiani M.
    Cohesion by topology: sister chromatids interlocked by DNA.
    Genes Dev. 2008 Sep 1;22(17):2297-301. doi:10.1101/gad.1719308. PMID: 18765785; PMCID: PMC2749673.
  79. Ohuchi T, Seki M, Branzei D, Maeda D, Ui A, Ogiwara H, Tada S, Enomoto T.
    Rad52 sumoylation and its involvement in the efficient induction of homologous recombination.
    DNA Repair (Amst). 2008 Jun 1;7(6):879-89. doi:10.1016/j.dnarep.2008.02.005. Epub 2008 Apr 8. PMID: 18396468.
  80. Branzei D, Foiani M.
    Regulation of DNA repair throughout the cell cycle.
    Nat Rev Mol Cell Biol. 2008 Apr;9(4):297-308. doi: 10.1038/nrm2351. Epub 2008 Feb 20. PMID: 18285803.
  81. Branzei D, Foiani M.
    Template switching: from replication fork repair to genome rearrangements.
    Cell. 2007 Dec 28;131(7):1228-30. doi:10.1016/j.cell.2007.12.007. PMID: 18160033.
  82. Branzei D, Foiani M.
    RecQ helicases queuing with Srs2 to disrupt Rad51 filaments and suppress recombination.
    Genes Dev. 2007 Dec 1;21(23):3019-26. doi:10.1101/gad.1624707. PMID: 18056418.
  83. Branzei D, Foiani M.
    Interplay of replication checkpoints and repair proteins at stalled replication forks.
    DNA Repair (Amst). 2007 Jul1;6(7):994-1003. doi: 10.1016/j.dnarep.2007.02.018. Epub 2007 Mar 26. PMID:17382606.
  84. Branzei D, Sollier J, Liberi G, Zhao X, Maeda D, Seki M, Enomoto T, Ohta K, Foiani M.
    Ubc9- and mms21-mediated sumoylation counteracts recombinogenic events at damaged replication forks.
    Cell. 2006 Nov 3;127(3):509-22. doi:10.1016/j.cell.2006.08.050. PMID: 17081974.
  85. Vijeh Motlagh ND, Seki M, Branzei D, Enomoto T.
    Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31.
    DNA Repair (Amst). 2006 Dec 9;5(12):1459-74. doi: 10.1016/j.dnarep.2006.07.006. Epub 2006 Sep 1. PMID: 16949354.
  86. Branzei D, Foiani M.
    The Rad53 signal transduction pathway: Replication fork stabilization, DNA repair, and adaptation.
    Exp Cell Res. 2006 Aug 15;312(14):2654-9. doi: 10.1016/j.yexcr.2006.06.012. Epub 2006 Jun 20. PMID: 16859682.
  87. Branzei D, Foiani M.
    The DNA damage response during DNA replication.
    Curr Opin Cell Biol. 2005 Dec;17(6):568-75. doi: 10.1016/j.ceb.2005.09.003. Epub 2005 Oct 13. PMID: 16226452.
  88. 87:
  89. Branzei D, Seki M, Enomoto T.
    Rad18/Rad5/Mms2-mediated polyubiquitination of PCNA is implicated in replication completion during replication stress.
    Genes Cells. 2004 Nov;9(11):1031-42. doi: 10.1111/j.1365-2443.2004.00787.x. PMID:15507115.
  90. Maeda D, Seki M, Onoda F, Branzei D, Kawabe Y, Enomoto T.
    Ubc9 is required for damage-tolerance and damage-induced interchromosomal homologous recombination in S. cerevisiae.
    DNA Repair (Amst). 2004 Mar 4;3(3):335-41. doi: 10.1016/j.dnarep.2003.11.011. PMID: 15177048.
  91. Branzei D, Seki M, Onoda F, Yagi H, Kawabe Y, Enomoto T.
    Characterization of the slow-growth phenotype of S. cerevisiae Whip/Mgs1 Sgs1 double deletion mutants.
    DNA Repair (Amst). 2002 Aug 6;1(8):671-82. doi:10.1016/s1568-7864(02)00073-3. PMID: 12509289.
  92. Branzei D, Seki M, Onoda F, Enomoto T.
    The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta.
    Mol Genet Genomics. 2002 Nov;268(3):371-86. doi: 10.1007/s00438-002-0757-3. Epub 2002 Oct 8. PMID:12436259.
  93. Kawabe Yi, Branzei D, Hayashi T, Suzuki H, Masuko T, Onoda F, Heo SJ, Ikeda H, Shimamoto A, Furuichi Y, Seki M, Enomoto T.
    A novel protein interacts with the Werner's syndrome gene product physically and functionally.
    J Biol Chem.2001 Jun 8;276(23):20364-9. doi: 10.1074/jbc.C100035200. Epub 2001 Apr 11. PMID:11301316.
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