IFOM

Publications G. V. Shivashankar

(2014-2017)

  1. Caroline Uhler & G.V.Shivashankar
    Nuclear mechano-genomics
    Nature Reviews Molecular Cell Biology, (invited review 2017 - under submission)

  2. Caroline Uhler & G.V.Shivashankar
    Chromosome intermingling as mechanical hotspots for genome regulation
    Trends in Cell Biology (invited review 2017 - under review)

  3. Bibhas Roy, Prasuna Rao and G.V.Shivashankar
    Geometric confinement of cells induce nuclear reprogramming
    (2017 ? under review)

  4. Aninda Mitra, Saradha.V. Pathy, Prasuna Rao and G.V.Shivashankar
    Cell-geometric-constraints differentially regulate TNFα-mediated gene expression programs
    Proceedings of the National Academy of Sciences-USA - (final revision, 2017)

  5. Yejun Wang, Mallika Nagarajan, Caroline Uhler and G.V.Shivashankar
    Cell geometry orients and repositions chromosomes to regulate genomic programs
    Molecular Biology of the Cell, (final revision, 2017)

  6. K. Radhakrishna, Saradha V. Pathy and G.V.Shivashankar
    Nuclear positioning and its translation dynamics is regulated by cell geometry
    Biophysical Journal (final revision, 2017)

  7. Yejun Wang, Prasuna Ratna and G.V. Shivashankar
    Superresolution imaging of nanoscale chromosome contacts
    Nature Sci Rep. (2017) 7:42422. doi: 10.1038/srep42422.

  8. V.Ruprecht, P.Monzo, A.Ravasio, Z.Yue, E.Makhija, P.O.Strale, N.Gauthier, G.V.Shivashankar, V.Studer, C.Albiges-Rizo, V.Viasnoff
    How cells respond to environmental cues - insights from bio-functionalized substrates.
    (2017) Journal of Cell Science 130:51-61.

  9. Caroline Uhler and G.V. Shivashankar
    Geometric control and modeling of genome reprogramming
    BioArchitecture. 2016 Jul 19:1-9.

  10. Ekta Makhija, Jokhun Kamal and G.V.Shivashankar
    Nuclear plasticity and telomere dynamics is modulated by extra-cellular matrix constraints
    Proceedings of the National Academy of Sciences-USA (2016) 113(1):E32-40.

  11. Naotaka Nakazawa, Aneesh R. Sathe, G. V. Shivashankar and Mike Sheetz
    Matrix Mechanics Controls FHL2 Movement to the Nucleus to Activate p21/CDKN1A Expression
    Proceedings of the National Academy of Sciences-USA (2016) 113(44):E6813-E6822

  12. Aneesh Sathe, G.V.Shivashankar and Mike Sheetz
    Nuclear transport of paxillin depends on focal adhesion dynamics and FAT Domains
    Journal of Cell Science (2016) 129(10):1981-8

  13. Shovamayee Maharana, K.Venkatesan Iyer, Nikhil Jain, Mallika Nagarajan, Yejun Wang and G.V.Shivashankar
    Chromosome intermingling - the physical basis of chromosome organization in differentiated cells
    Nucleic Acids Research, (2016) doi: 10.1093/nar/gkw131

  14. Yejun Wang, Ekta Makhija, Karthik Damodharan and G.V.Shivashankar
    Role of Cell Geometry on Nuclear Mechanics, Chromosome Reorganization, and Gene Expression
    Molecular and Cellular Mechanobiology (2016, Edited by Chien, Engler and Wang), Springer Press.

  15. Ramdas NM, Qingsen Li, Shivashankar GV
    Regulation of nuclear morphology by actomyosin components and cell geometry.
    IEEE Eng Med Biol Soc. 2015:342-5.

  16. Shao X, Kawauchi K, Shivashankar GV, Bershadsky AD.
    Novel localization of formin mDia2: importin β-mediated delivery to and retention at the cytoplasmic side of the nuclear envelope.
    Biol Open. 2015 4(11):1569-75.

  17. Kee Chua Toh, Nisha Ramdas and G.V.Shivashankar
    Actin cytoskeleton differentially alters the dynamics of lamin A/C, HP1α and H2B core histone proteins to remodel chromatin condensation state in living cells
    Integrative Biology, 2015 (10):1309-17.

  18. Xiaowei Shao, Li Qingsen, Alexandar Mogilner, Alexandar Bershadsky and G.V.Shivashankar
    Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim
    Proceedings of the National Academy of Sciences-USA (2015) 112(20):E2595-601

  19. Li Qingsen, Ekta Makhija, F.M. Hameed and G.V.Shivashankar
    Micropillar displacements by cell traction forces are mechanically correlated with nuclear dynamics
    Biochemical and Biophysical Research Communications, (2015) 461(2):372-7

  20. Nisha M Ramdas and G.V.Shivashankar
    Cytoskeletal control of nuclear morphology and chromatin organization
    Journal of Molecular Biology (2015) 427(3):695-706

  21. Yejun Wang, Shovamayee Maharana, Michelle Wang & G.V.Shivashankar
    Super-resolution microscopy reveals decondensed chromatin structure at transcription sites
    Nature Sci Rep. (2014) Mar 26;4:4477

  22. Ananyo Maitra, Madhuresh Sumit, Sriram Ramaswamy & G.V. Shivashankar
    Acto-myosin contractility rotates the cell nucleus Abhishek Kumar
    Nature Sci Rep. 2014 Jan 21;4:3781

  23. Amit Kumar, Michele Mazzanti, Martin Mistrik, Galina Beznusenko, Alexandre Mironov, Massimiliano Garre, Dario Parazzoli, G.V. Shivashankar, Giorgio Scita
    ATR mediates a mechanical checkpoint at the nuclear envelope in response to membrane stress.
    Jiri Bartek and Marco Fioni (2014) Cell, 158, 633-646

  24. Pan CQ, G.V.Shivashankar, Bershadsky A, Sudol M, Sheetz M.
    Yap-Taz as mechanosensors and mechanotransducers in regulating organ size and tumor growth Low BC
    (2014) FEBS Lett. 19;588(16):2663-2670

  25. Wong Cheng Lee, Hui Shi, Zhiyong Poon, Lin Myint Nyan, Tanwi Kaushik, G V. Shivashankar, Jerry K Y Chan, Chwee Teck Lim, Jongyoon Han & Krystyn J. Van Vliet
    Multivariate biophysical markers predictive of mesenchymal stromal cell multipotency
    Proceedings of the National Academy of Sciences-USA (2014) Oct 21;111(42):E4409-18

  26. Ekta Makhija, K. Venkatesan Iyer, Shefali Talwar & G.V.Shivashankar
    Probing Chromatin Structure and Dynamics Using Fluorescence Anisotropy Imaging
    CRC Handbook, Imaging Biological Mechanics (2014)

  27. M.Garg, N.Ramdas, M.Vijayalakshmi, G.V.Shivashankar, A.Sarin
    The C-terminal domain (CTD) in linker histones antagonizes anti-apoptotic proteins to modulate apoptotic outcomes at the mitochondrion.
    Cell Death & Disease (2014) 5:e1058.

  28. Garg M, Perumalsamy LR, G.V.Shivashankar, Sarin A.
    The linker histone H1.2 is an intermediate in the apoptotic response to cytokine deprivation to T-cell effectors
    Int J Cell Biol. (2014): 674753

  29. Shefali Talwar, Nikhil Jain & G.V.Shivashankar
    The regulation of gene expression during onset of differentiation by nuclear mechanical heterogeneity
    Biomaterials. (2014) 35, 2411-19

  30. Li Qingsen, Abhishek Kumar, Ekta Makhija & G.V.Shivashankar
    The regulation of dynamic mechanical coupling between actin cytoskeleton and nucleus by matrix geometry
    Biomaterials. (2014) 35, 961-69.