Investigating, modelling and understanding
the genome in space and time

May 9-11, 2023 - IFOM, Milan (IT)


Tuesday, May 9

8:30-9:20 Registration
9:20-9:30 Welcome introduction by the organizers
9:30-10:00 Invited speaker talk
Nick Gilbert | MRC Human Genetics Unit at the University of Edinburgh, UK
Chromosome structure regulated by a transcription
10:00-10:20 Talk selected from abstracts
Léa Costes | Centre de Biologie Intégrative, Toulouse, France
Physical principles underlying chromatin dynamic changes in response to transcription activation
10:20-10:40 Talk selected from abstracts
Ramveer Choudhary | IFOM ETS - The AIRC Institute of Molecular Oncology
Genomic elements mediating inter and intra chromosomal interactions
10:40-11:00 Talk selected from abstracts
Francesca Rossi | Max Planck Institute for Molecular Genetics
Connecting the Dots: PHF13 and cohesin promote higher chromatin order
11:00-11:40 Coffee Break
11:40-12:10 Invited speaker talk
Barbora Kozlikova | Faculty of Informatics, Masaryk University, Brno, Czech Republic
Chromoskein: 3D representation of chromatin structure.
12:10-12:30 Talk selected from abstracts
Davide Mazza | San Raffaele Scientific Institute, Milan
Impact of chromatin organization on the search mechanism of nuclear factors; a single molecule study.
12:30-12:50 Talk selected from abstracts
Irene Farabella | Istituto Italiano di Tecnologia
Investigating genome plasticity at the nanoscale.
12:50-13:15 Flash Talks selected from abstracts
Alessandro Bertero | University of Torino
Dafne Campigli Di Giammartino | Istituto Italiano di Tecnologia, Genova
Mattia Conte | Physics Dept. Università di Napoli
Takashi Nishio | Technical University of Dresden
Alex Chen Yi Zhang | SISSA, Trieste
13:30-14:30 Lunch break
14:30-16:00 Poster session
16:00-16:30 Coffee Break
16:30-17:00 Invited speaker talk
Jan Huertas | Rosana Collepardo Lab, Department of Chemistry, University of Cambridge, UK
Multiscale Simulations of Chromatin
16:30-16:50 Talk selected from abstracts
Hulkar Mamayusupova | University of Essex
Nucleosome repositioning in cancer and cell differentiation
17:20-17:40 Talk selected from abstracts
Michele Di Pierro | Dep. of Physics, Northeastern University, Boston, MA
Landscapes of Genomic Architecture Across Evolution
17:40-18:00 Talk selected from abstracts
Flavia Corsi | IMBA - Institute of Molecular Biotechnology
Sister chromatid cohesion in human replicated chromosomes is asymmetric
18:00-18:30 Invited speaker talk
Elisa Oricchio | Swiss Institute of Experimental Cancer Research and EPFL, Lausanne, Switzerland
Modulation of 3D chromatin structures to support tumor evolution

Wednesday, May 10

9:30-10:00 Invited speaker talk
Mario Nicodemi | Physics Dept. Università "Federico II" and INFN, Napoli, Italy; MDC, Berlin, Germany
Loop-extrusion & phase separation in chromatin folding
10:00-10:20 Talk selected from abstracts
Federica Lucini | IFOM ETS - The AIRC Institute of Molecular Oncology
Biochemical properties of chromatin read by 4f-SAMMY-seq: mapping of euchromatin, heterochromatin and their 3D compartmentalization
10:20-10:40 Talk selected from abstracts
Juan Pablo Arcon | IRB Barcelona
Cell-to-cell structural variability on chromatin models
10:40-11:00 Talk selected from abstracts
Sophie Klempahn | Cluster of Excellence Physics of Life, Technical University of Dresden
Changes in the nucleosome positioning by chromatin remodelers
11:00-11:40 Coffee Break
11:40-12:10 Invited speaker talk
Giovanni Ciriello | University of Lausanne, Switzerland
Chromatin plasticity across cell types and haplotypes
12:10-12:30 Talk selected from abstracts
David Brückner | Institute of Science and Technology Austria
Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome
12:30-12:50 Talk selected from abstracts
Jonas Paulsen | University of Oslo
Modeling loop extrusion dynamics genome wide
12:50-13:10 Talk selected from abstracts
Vera Pancaldi | INSERM U1037 Centre de Recherche en Cancèrologie de Toulouse
Exploring the relation between evolutionary gene age, gene expression variability and chromatin 3D structure in cancer
13:10-13:30 Talk selected from abstracts
Pavel Kos | FMI for biomedical research
Cohesin and CTCF orchestrate chromosome dynamics
13:30-14:30 Lunch break
14:30-16:30 Free time
16:30-17:00 Coffee Break
17:00-17:30 Invited speaker talk
Mikhail Spivakov | MRC London Institute of Medical Sciences, London, UK
Probing the relationship between enhancer activity, connectivity and gene expression
17:30-17:50 Talk selected from abstracts
Amith Zafal Abdulla | ENS de Lyon, France
“Living Painter”: Modeling the dynamic coupling between epigenome regulation and 3D chromatin organization
17:50-19:30 Poster session
19:30 Social aperitivo/light dinner

Thursday, May 11

9:30-10:00 Invited speaker talk
Antoine Coulon | Institut Curie and CNRS, Paris, France
Understanding interphase chromosomes as physical objects
10:00-10:20 Talk selected from abstracts
David Lleres | CNRS/University of Montpellier/ IGMM
Evidence for Low Nanocompaction of Heterochromatin in Living Embryonic Stem Cells
10:20-10:40 Talk selected from abstracts
Vittore Scolari | Institut Curie
Forces driving chromatin in the nucleus
10:40-11:00 Talk selected from abstracts
Samuel Zambrano | School of Medicine, Vita-Salute San Raffaele University
Role of genome spatial organization in transcription factor induced gene expression: insights from the NFkB system
11:00-11:40 Coffee Break
11:40-12:10 Invited speaker talk
Vasily Zaburdaev | Friedrich-Alexander Universität Erlangen-Nürnberg and Max-Planck-Zentrum für Physik und Medizin, Erlangen, Germany
Microphase separation and surface condensation as biophysical mechanisms of transcriptional organisation
12:10-12:30 Talk selected from abstracts
Peter Meister | University of Bern
Formation of fountains by cohesin in nematodes: micro-TADs for the limitation of enhancer search space?
12:30-12:50 Talk selected from abstracts
Cristina Fracassi | Vita-Salute San Raffaele University
PML instructs chromatin composition towards expression of pro-metastatic genes in triple-negative breast cancer
12:50-13:20 Invited speaker talk
Magda Bienko |Human Technopole, Milan, Italy and Karolinska Institutet, Stockholm, Sweden
FRET-FISH allows us to measure local DNA compaction at specific DNA loci
13:20-13:30 Concluding remarks
13:30 Lunch and departure

Download the program.

(Last update May, 06 2023)

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