XX Italian Drosophila Research Conference

March 6-8, 2024 - IFOM, Milan (IT)

About The Conference


This traditionally biannual meeting comes back in its twentieth edition after a break due to the covid pandemic.
The aim of this meeting is to gather researchers working in Italy at all career stages that use Drosophila melanogaster as model organism across research fields.
This meeting promotes exchange of results, ideas, expertise and tools in a friendly setting, and constitutes an important occasion to establish new collaborations or consolidate existing ones. It also provides the possibility for Italian drosophilists working abroad to share their experience with colleagues in Italy.

Invited Speakers

Florence Besse Institut de Biologie Valrose, Nice

Aurelio Teleman DKFZ, Heidelberg

Program Committee

Thomas Vaccari University of Milan

Simona Polo IFOM ETS and University of Milan

Erika Donà CNR - Institute of Neuroscience


Keynote 1 - Prof.Dr.Aurelio Teleman, DKFZ, Heidelberg, Germany

Regulation of tissue size

Session 1 - Mechanisms of tumorigenesis

Chair - Andrea D’Alessandro & Valeria Specchia

Anna Frappaolo, IBPM CNR, Rome

GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila

Simona Totaro, University of Milan, Milan

In vivo effects of pharmacologic and genetic PARP inhibition on Cohesinmediated phenotypes using Drosophila melanogaster

Giulia Tesoriere, University of Rome La Sapienza

Vitamin B6 deficiency cooperates with oncogenic ras to induce malignant tumors in Drosophila

Susumu Hirabayashi, MRC Laboratory of Medical Sciences, London, UK

Exploring host-tumour metabolic interactions

Coffee Break

Session 2 - Environment,physiology and disease

Chair - Giulia Tesoriere & Alessia Soldano

Maria Dolores De Donno, University of Salento, Lecce

SAPK signalling activation and functional impairment in cadmium stressed fly brains

Patrizia Morciano, University of L’ Aquila, L’ Aquila

In vivo underground radiobiology at INFN-Laboratori Nazionali del Gran Sasso

Simona Del Quondam , Tuscia University, Viterbo

Modeling of second-generation antipsycotic-induced metabolic alterations in the fruit fly Drosophila melanogaster

Nadia Ceccato, University of Padua, Padua

Drosophila melanogaster as a model to investigate the link between circadian clock and neurodegenerativedisorders

Luca Valzania, Institut Curie, Paris

A temporal allocation of amino acid resources ensures fitness and body allometry

Social dinner

Session 3 - Shaping the nervous system

Chair - Nadia Ceccato & Laura Ciapponi

Alessia Soldano, SISSA,Trieste

Deciphering the role of the epitranscriptomic modification m6A in glia during brain development

Erika Donà, CNR IN, Milan

Mapping the developmental transcriptomic atlas of the nerve cord to its connectome

Maria Patrizia Somma, CNR-IBPM, Rome

Chromatin alteration and lamin dysfunction in primary microcephaly Drosophila models

Simona Polo, IFOM, Milan

HECW1: navigating the nexus of neurodevelopment and neurodegeneration


Session 4 - Neurodegeneration

Chair - Liliana Tullo & Luca Valzania

Ruben Cauchi, University of Malta, Msida

Linking Genetic Risk Factor SCFD1 to ALS Pathophysiology

Laura Ciapponi, University of Rome, Rome

Suv3-9 mediated methylation controls Age-Related TDP-43 Decline, Triggering neurodegeneration

Davide Colaianni, University of Padua, Padua

miR-210 is essential to retinal homeostasis in fruit flies and mice

Giuliana Cesare, University of Milan, Milan

The role of the E3 ubiquitin ligase Hecw in autophagy

Cosimo Sabino, University of Trento, Trento

Rapamycin deregulated genes as new potential targets of antiaging interventions

Elena Ziviani , University of Padua, Padua

Mitophagic effectof USP14 inhibition rescues circadian defects and sleep disturbance of an in vivo model of Parkinson's disease

Sponsor talk


Session 5 - In vivo mechanobiology

Chair - Livia Scatolini & Antonio Galeone

Francesco Napoletano, University of Trieste, Trieste

Exploring the impact of mechanical stress in neurodegeneration

Alessandro Scopelliti , University of Edinburgh, Edinburgh, UK

The mechanosensitive channel Piezo delays epidermal wound closure to ensure effective inflammatory response and restoration of epithelial integrity

Matteo Rauzi, University Côte d'Azur, Nice, France

Nuclear migration controls the activity of cortical actomyosin networks powering tissue morphogenesis

Visit to Fondazione Prada

Session 6 - Disease models

Chair - Simona Del Quondam & Francesco Napoletano

Antonio Galeone, CNR-Nanotech, Lecce

Role of glycosylation-related genes in signaling pathways and diseases

Gaia Consonni, University of Milan, Milan

The role of nutritional intervention and of the microbiota in a Drosophila model of NGLY deficiency

Andrea D'Alessandro, University of Rome, Rome

A novel inherited TBX3 missense variant is associated with a prenatal case of ulnar mammary syndrome and induces development defects when expressed in Drosophila

Giulia Vitale, University of Milan, Milan

An in vivo model of intractable R257C-ACTG2 Visceral Myopathy to study pathogenesis and to identify new disease targets

Damiano Guerrini, University of Rome, Rome

Investigating transcriptional stress in Drosophila model for SMA


Session 7 - Inside the cell

Chair - Damiano Guerrini & Elena Ziviani

Liliana Tullo, University of Rome, Rome

Assessing an unprecedented role for Heterochromatin Protein 1a (HP1a) at mitochondria

Livia Scatolini, University of Rome, Rome

Live imaging analysis of mutations affecting chromosome stability in drosophila embryos

Valeria Manara, University of Trento, Trento

Reduction of nucleolar NOC1 induces MYC-dependent nucleolar stress and p53 upregulation: a novel response to ribosomal biogenesis impairments

Manuela Santalla, CNR-Neuroscience Institute, Padua

Endoplasmic/Sarcoplasmic Reticulum shaping impacts on intracellular calcium handling in Drosophila melanogaster

Keynote - 2 Florence Besse, iBV, Nice - France (remote connection)

Regulating RNA in space and time in the fly nervous system

Prizes and concluding remarks

Event Venue

Conference Room
Via Adamello 16 Milan


Registrations opening 27th November, 2023
Registrations are now closed
Registrations fee: € 150,00

Registration procedure

  • In the first step all participants are requested to fill the registration form
  • Shortly after, participants will receive indication by email to pay the registration fee
  • Participants that have submitted an abstract will be notified by mid-February about the possibility of an oral presentation

The registration fee includes

  • Attendance to all the scientific sessions of the Symposium
  • Meals and coffee breaks during the sessions
  • Social events (aperitivo and visit to Fondazione Prada)
  • Symposium material

Travel and lodging expenses will be at each participant's charge
The registration fee is not refundable


A list of hotels located close to the conference venue. Please make your reservation directly with the hotel.

Grand Visconti Palace****
Viale Isonzo, 14 - 20135 Milano | Ph.:+39 02 540341 | email: info@grandviscontipalace.com | web site

BEST WESTERN Hotel Major****
Viale Isonzo, 2 - 20135 Milano | Ph.: +39 02 55188335 | email: reserv@hmajor.it | web site

Via dei Fontanili, 26 -20141 Milano | Ph.: +39 02 39831433 | email: info@mihotel.it | web site

Via Rutilia, 6 - 20141 Milano | Ph.: +39 02 55212838 / +39 02 537368 | email: info@gardenmilano.it | web site

Madama Hostel & Bistrot
Via Benaco, 1 - 20139 Milano | Ph.: +39 02 36727370 | email: info@madamahostel.com | web site

Contact Us


Via Adamello 16, Milan